ஆஞ்சியோலஜி: திறந்த அணுகல்
திறந்த அணுகல்

சுருக்கம்

Assesment of Autonomic Function in Slow Coronary Flow using Heart Rate Variability and Heart Rate Turbulence

Savas Sarıkaya, Fatih Altunkas, Kayıhan Karaman, Safak Sahin, Lutfu Akyol, Elif Borekci and Yunus Keser Yılmaz

Background: Slow Coronary Flow Syndrome (SCFS) is an angiographic observation characterized by angiographically normal or near-normal coronary arteries with the delayed progression of contrast dye injected into the coronary tree. Previous studies suggested that these patients had autonomic dysfunction. Life threatening arrhythmias and sudden cardiac death have also been reported in these patients.

Aim: Our aim was to assess autonomic function in slow coronary patients using heart rate variability and heart rate turbulence.

Method: We selected 40 slow coronary patients and 30 healthy individuals with normal coronary. 24 hours ambulatory holter ECG recordings were obtained from all patients. Turbulence onset (TO), Turbulence slope (TS), Time domain HRV (SDNN, Mean RR, RMSSD, Pnn50 and triangular index (TI) were analysed and compared between two groups.

Results: There were no difference in Mean RR (ms), RMSSD (ms) and Total Snn50 between groups. But SDNN (ms) and Triangular index (TI) were different between groups.( 128.52 ± 9.32 vs 174.25 ± 73 p<0.001 and 31.74 ± 4.67 vs 42.48 ± 5.86 p<0.001 respectively). TO and TS were different between groups (1.06 ± 2.4 vs -0.16 ± 0.34 p: 0.009 and 9.47 ± 6.03 vs 14.41 ± 8.66 p: 0.021). There was a negative correlation between SDNN and mean TFC (r: -0.834 p<0.001) and positive correlation between TO and mean TFC (r:0.350 p:0.003).

Conclusion: We showed that some of HRV parameters and HRT was impaired in favor of slow coronary patients. Impaired autonomic activity may lead to the tendency to arrhythmias and may cause sudden cardiac death in slow coronary patients.