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Periphreal T-Cell Lymphoma not otherwise specified (PTCL-NOS) Variety in A 58 Year Old Male Patient in Oncology Ward J.P.M.C. Karachi: A Case Report

Fahad Khan, Ghulam Haider, Hassan Ahmed and Rekha Jiswant

Background: Peripheral T cell Lymphoma is a heterogeneous form of non-hodgkin lymphoma, and encompasses many sub-types of which Peripheral T cell lymphoma not otherwise specified (PTCL-NOS) is the rare subset.

Case presentation: A 58 years old farmer presented with multiple small to medium sized pruritic skin swellings on whole scalp, neck, face and inguinal region with bilateral axillary lymphadenopathy, patient denied any constitutional symptoms or rash. Tissue biopsy reported solid sheets of large atypical pleomorphic cells; Immunohistochemistry and histopathology findings favored the diagnosis of Peripheral T-cell Lymphoma Not Otherwise Specified. CT scan of brain, chest and abdomen excluded visceral involvement.

Conclusion: This group of PTCL is aggressive in nature and requires standard combination chemotherapy upon diagnosis, through this report we highlight the variability of Peripheral T Cell Lymphoma’s clinical presentation.