மருத்துவ குழந்தை மருத்துவம்: திறந்த அணுகல்
திறந்த அணுகல்

சுருக்கம்

Spectrum of Congenital Heart Diseases in Children with Down Syndrome in Ajdaybia, Libya

Rugea Mahmud Mahmmed

Down syndrome: Is by far the most common and best known chromosomal disorder in humans.

Aim of study: T o def ine the fr eq uency and patt erns of congenit al hear t disease among childr en with down syndrome in Ejdabyia North eastern of Libya.

Patients and methods: This is prospective descriptive study include all phenotypic down syndrome children referred to Echo department at AL-Mugref Teaching Hospital, North eastern of Libya. Verbal consent was taken from guardiants of all participants using GE Vivid S5 Echo Machine.

Results: Out of 813 cases 50 (6.1%) case were down syndrome included in our study. 29 (58%) them were female and 21 (42%) were male with Female : Male ratio 1:3:1. 46 (92%) of cases have congenital heart disease. where 40 (87%) have single cardiac defect and the most common defect was AV Canal 27 (54%) case and other form include ASD 6 (12%), VSD 3 (6%), PDA 3(6%) and TOF 1 (2%). the combined lesions were present in 6 (13%) cases include 3(6%) (TOF+AV Canal) and 3 (6%) (VSD+ASD+PDA).

Conculsion: Highly prevalence of CHDs among Down syndrome patients with Female dominance. AV Canal was the most common Congenital Heart lesions. So, important to early referral and screening for CHDs in DS.