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Specific Probiotic Combination Exerts a Synergistic Effect against Antibiotic-Associated Diarrhea during and After an Antibiotic Therapy: A Randomized Double-Blind Placebo Controlled Trial

Greet Vanheule*, Gregoire Wieers, An-Katrien Vynckier, Mieke Van Den Driessche

Antibiotic treatments have been associated with the alteration of the microbiota and the killing or growth suppression of antibiotic-sensitive bacteria, with as result an overgrowth of opportunistic and resistant bacteria. This intestinal disbalance can be linked to clinical symptoms such as antibiotic-associated diarrhea (AAD) that can occur up to 8 weeks after antibiotic treatment.