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Renal Denervation Therapy: The Evolving Treatment of Hypertension and How African Americans Stand to Benefit

Baran Aksut and Chante Karimkhani

Renal Denervation Therapy has shown promise in treating resistant hypertension. Hypertension in African Americans, which occurs more often and at an earlier age compared to whites and Hispanics, has a prevalence of approximately 43.0% and 45.7% for men and women, respectively. After exploring the various pathophysiological mechanisms of hypertension, specifically the pathways affecting the black population, this paper proposes that renal denervation therapy will have a significant impact on the management of resistant hypertension in this cohort of patients. It will be important for future trials to include certain subgroups of the population so as to maximize any benefits that are seen from this therapy and tailor them to each patient appropriately.