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How much Damage can make the Glucose in Cancer?

Montero S, Durán I , Pomuceno-Orduñez JP , Martín RR , Mesa-Alavaréz MD , Mansilla R, Cocho G and Nieto-Villar JM

Using the entropy production rate method to determine the influence of glucose on a glycolysis model for HeLa tumor line, the greater complexity and robustness hypoglycemic phenotype was established. On the other side, inside the same metabolic phenotype a higher glucose concentration corresponds to a higher entropy production rate. It is concluded that this behavior is indicative of the directional character and stability of the dynamical behavior of cancer glycolysis.