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Endocrinology 2017: Interactivity among calcium metabolism and anti-reflux remedy after sleeve gastrectomy

Christoph Sperker

Malabsorption and micronutrient deficiencies are known troubles after bariatric surgery. Therefore, suppl]ementation and regular controls are inevitable. Calcium (Ca2+) tiers, which may be disrupted after malabsorptive bariatric strategies are acknowledged to rely on gastric pH degrees. To determine the impact of proton pump inhibitors (PPI) on Ca2+, parathyroid gland hormone (PTH) and nutrition D stages after sleeve gastrectomy (SG). All sufferers who underwent SG between 2008 and 2013 were enrolled in our follow-up program. The patients were tested preoperatively and then 4 times at some stage in the first 12 months. Ca2+ metabolism and weight parameters were monitored. All the sufferers received 3000 mg of Ca2+ carbonate (equal to 1200 mg of Ca2+), 800 IE of vitamin D, in addition to one multivitamin pill daily. All the parameters were then analyzed for institutions with PPI intake. Results: Data of 385 out of 400 (96.2%) sufferers were analyzed after 1 year of follow-up (3.8% misplaced to follow-up). Thirty nine (10.1%) sufferers took PPI for at the least three months during the first year. The Ca2+ levels were notably lower (p<0.0001)in the PPI group in comparison to the non-PPI group, although neither of the groups showed hypocalcaemia. The PTH levels showed an opposite behavior (p<0.0001).