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Worsening of Anxiety Symptoms with Antipsychotic Treatment in a Patient Misdiagnosed with Schizoaffective Disorder

Shad Mujeeb U

Obsessive compulsive symptoms (OCS) can easily mimic psychosis, which raises the risk for misdiagnosis of obsessive compulsive disorder (OCD) with a primary psychotic disorder, such as schizoaffective disorder. Although both OCD and schizoaffective disorder can be effectively treated with psychotropic medications, a misdiagnosis can result in an inappropriate pharmacotherapy. Here we describe a case of a young patient, who was misdiagnosed with schizoaffective disorder and was treated with multiple second-generation antipsychotic medications (SGAMs) with significant adverse effects, further worsening of OCS and no improvement in psychosis. Patient exhibited remarkable improvement in his OCS, adverse effects and psychosis after he was switched from his SGAM to sertraline, an approved treatment for OCD.