ஜர்னல் ஆஃப் பார்மாசூட்டிகல் கேர் & ஹெல்த் சிஸ்டம்ஸ்
திறந்த அணுகல்

சுருக்கம்

Should Medications be Coadministered with Albumin in Hypoalbuminemic Patients

Serlemitsos Day M, Ellington K, Akalu A and Uweh K

Protein binding significantly influences pharmacokinetic properties of drug distribution. Albumin accounts for approximately 60% of the total plasma protein by mass, thereby making it the major protein in the body. Hypoalbuminemia, a type of hypoproteinemia, is a condition of abnormally low blood albumin levels. Hypoaluminemia causes pharmacokinetic issues in regards to dosing a patient's medication. The purpose of this paper is to review the role of the coadministration of albumin in hypoalbuminemic patients to optimize pharmacotherapy.