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Pharmacokinetic Drug-Drug Interplay and their Implication in Scientific Management

Amritha Pritham*

In particular, poly-therapy increases the complexity of healing management and thereby the danger of clinically crucial DDIs, which could each induce the improvement of negative drug reactions or lessen the clinical efficacy. DDIs may be classify into major companies: pharmacokinetic and pharmacodynamic. In this assessment, the use of Medline, PubMed, Embase, Cochrane library and Reference lists we searched articles posted, and we defined the mechanism of pharmacokinetic DDIs focusing the interest on their clinical implications.