select ad.sno,ad.journal,ad.title,ad.author_names,ad.abstract,ad.abstractlink,j.j_name,vi.* from articles_data ad left join journals j on j.journal=ad.journal left join vol_issues vi on vi.issue_id_en=ad.issue_id where ad.sno_en='40389' and ad.lang_id='10' and j.lang_id='10' and vi.lang_id='10' Synthesis, Characterization, Anticancer, DNA Binding and Ant | 40389
புற்றுநோய் அறிவியல் மற்றும் ஆராய்ச்சி இதழ்

புற்றுநோய் அறிவியல் மற்றும் ஆராய்ச்சி இதழ்
திறந்த அணுகல்

ஐ.எஸ்.எஸ்.என்: 2576-1447

சுருக்கம்

Synthesis, Characterization, Anticancer, DNA Binding and Antioxidant Studies of Benzylamine Supported Pd (II) Complex

Nitin Kumar Sharma, Rakesh Kumar Ameta and Man Singh

A benzylamine supported palladium (II) complex has been synthesized and characterized using different spectroscopic techniques, such as FTIR, UV/Vis., 1H, 13C NMR and LCMS. The semi crystalline nature of the complex was investigated through powder XRD and SAED pattern analysed by HRTEM. The in vitro biological study against breast cancer cell lines MCF-7 and MDA-MB-231 was not much effective but their strong DNA binding activity (DBA) compared to free ligand suggested them as a good DNA binder and makes them interesting against other cancerous cell lines. The DBA further supported by physicochemical studies such as surface tension and viscosity of complex+DNA which inferred the disruption and intercalation of DNA and complex. The scavenging activity (SA) also proves the anticancer nature of complex, in this context, the scavenging activity of complex was determined through DPPH• free radical and the result indicates good antioxidant behaviour of complexes.

மறுப்பு: இந்த சுருக்கமானது செயற்கை நுண்ணறிவு கருவிகளைப் பயன்படுத்தி மொழிபெயர்க்கப்பட்டது மற்றும் இன்னும் மதிப்பாய்வு செய்யப்படவில்லை அல்லது சரிபார்க்கப்படவில்லை.
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