உயிரியல் & மருத்துவத்தில் மேம்பட்ட நுட்பங்கள்
திறந்த அணுகல்

சுருக்கம்

Non-coding Vibration in Circadian Oscillation

Utpal Bhadra*, Pradipta Patra and Manika Pal-Bhadra

Neuron driven physiological activities such as sleep, feeding, energy consumption are controlled by light sensitive central clock genes in the pacemaker neurons in the brain. Multiple epigenetic events including post-transcriptional regulation, splicing, polyadenylation, mature mRNA editing and stability of translation products are the main vibrators for circadian oscillation with the instructive role of various sets of non-coding small regulatory RNA. Here, we sum up the basic role of small regulatory RNA and their epigenetic circuits in brain clock activity.