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Investigation of Three Different Treatment Planning Systems Using Intensity Modulated Radiotherapy Treatment Technique in Low-Grade Prostate Cancer: Dosimetric Comparison

Mehmet Sinan Karabey, Aysegul Unal Karabey*, Melis Teke, Aykut Oguz Konuk, Gulsah Ozkan, Berna Tirpanci, Ersan Yilmaz, Gorkem Aksu

Objective: The aim of this study is to compare the dosimetric differences of 3 different treatment planning systems and to examine the quality of the plan in low grade prostate cancer.

Method: 50 randomly selected low grade prostate cancer treatment plans using 3 different Treatment Planning Systems (TPS), Eclipse V13.6 (varian medical systems, Palo Alto USA), Prowess Panther V5.2 (Prowess Inc. Concord, CA, USA) and Raystation V2.4.8. (laboratories AB, Stockholm, Sweden) treatment planning systems. IMRT plans were made with Multi-Static Segment (MSS) Intensity Modulated Radiotherapy (IMRT) and Dynamic Multi-Leaf Collimator (DMLC) technique in 7 fields with 78 Gy conventional treatment radiation dose in 39 fractions with an increase of 50-51 degrees. PTV target volume and critical organ doses, Monitor Units (MU), PTV conformity index and homogeneity index values were examined.

Conclusion: Comparable dose distribution was achieved with IMRT plans created with the same planning Computed Tomography (CT) data in three different planning systems, and Dose Volume Histogram (DVH) data suitable for clinical use were obtained. When the homogeneity values were examined, there was a significant difference in favor of Raystation TPS (p<0.05). The prescribed dose that best covered the PTV volume was obtained with the Eclipse treatment planning station (p<0.05). In terms of critical organ doses, all planning systems met the desired criteria and there was no significant difference between criticle organ doses (p>0.05). More monitor units were obtained with Eclipse TPS than raystation and prowess TPS.