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Familial Mediterranean fever Attack during COVID-19 Infection and After COVID-19 Vaccination

Bekir Torun, Fatih Albayrak, Burak Okyar, Metin Kılınç, Fatih Yıldız, Gözde Yıldırım Çetin

Coronavirus disease 2019 (COVID-19), the novel coronavirus pneumonia, was caused by Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). SARS-CoV-2 causes of severe pneumonia in human. The general symptoms observed in the infected individuals are fever, cough, dyspnea and lesion in the lungs. In the advanced stage, the symptoms of this virus show pneumonia which progresses to severe pneumonia and acute respiratory distress syndrome. Familial Mediterranean Fever (FMF) and COVID-19 show a remarkable overlap of clinical symptoms and similar laboratory findings. Both are characterized by fever, abdominal/chest pain, elevation of C-reactive protein, and leukocytosis. Our case presents acute attacks of FMF during COVID-19 infection and after COVID-19 vaccination. This case is important because it is the first case of FMF attack after vaccination.