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Aspergillus Endophthalmitis in a Patient on Corticosteroid Therapy: A Case Report

Mohammed Cherkani Hassani, S Hakami, P Eghbal Afsari, P Le Roux, D Lipski, E Motulsky, P Sabbe, K Nacima

The case study is regarding a 50-year-old patient who had been undergoing corticosteroid therapy for renal disease. The patient was referred to Erasme Hospital due to a significant and a progressive decline in visual acuity in his left eye and was hospitalized for the management of uveitis, a condition characterized by inflammation of the uvea, which is the middle layer of the eye. Further investigations revealed a rare etiology i.e., Aspergillosis endophthalmitis. Endophthalmitis refers to inflammation within the eyeball, and in this case, it was associated with an infection caused by the fungus Aspergillus. Aspergillosis endophthalmitis is an infrequently reported clinical presentation in patients considered to be at risk of invasive aspergillosis. The association between corticosteroid use and the occurrence of aspergillosis endophthalmitis underscores the importance of considering the potential side effects and complications associated with immunosuppressive treatments. It also highlights the need for vigilance in monitoring patients who are at an increased risk of fungal infections, especially with unusual symptoms such as a drastic decrease in visual acuity.