மயக்க மருந்து & மருத்துவ ஆராய்ச்சி
திறந்த அணுகல்

சுருக்கம்

Early Cognitive Functions in Patients after Embolization in Neuroradiological Suite – A Comparison of Two Anesthetic Techniques

Sachidanand Jee Bharati, Charu Mahajan, Hemanshu Prabhakar, Keshav Goyal, Tumul Chowdhury and Ajai Chandra

Background: Less is known about prevalence of postoperative cognitive dysfunction after neurosurgical procedures. A Hindi version of Mini Mental State Examination (HMSE) is widely used for illiterate Hindi speaking population in the Indian subcontinent for assessment of cognitive dysfunction. The aim of the study was to assess effects of anesthetics on neurocognitive function in patients undergoing interventional procedure in neuroradiological suite. Methods: Twenty five patients with intracranial arterio-venous malformations and cerebral aneurysms were randomized to receive intravenous (propofol) or inhalational anesthetic (isoflurane). HMSE was performed in the ICU at 1 hour and 24 hours of tracheal extubation. Results: Baseline demographics like age and weight of patients differed significantly between the groups; however their cognitive functions were comparable. Intraoperative hemodynamic parameters like heart rate and mean arterial pressure were comparable between the two groups. Cognitive functions noted at the two time intervals in the postoperative period were also comparable between the two groups. Conclusion: We observed that anesthetic technique did not affect post embolization cognitive function, but, a better hemodynamic stability was maintained with total intravenous anesthesia.