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Uranium Exposure to a Community Population: Renal Proximal Tubule

Susan M Pinney

Uranium a radioactive element and a source of radioactive pollution directly influence the humans those are exposed to it. Sometimes high uranium content is present in phosphate rock used for the manufacturing of fertilizer. Besides being heaviest naturally occurring metal, uranium is one of the primeval radionuclides that can be found in low levels within all rocks, soil and water. In the record of history never has a scientific discovery so profoundly affected the course of human fate as the discovery of atomic energy. Therefore, its potential for destruction is massive and its use for economic purpose is limitless. In present era, rightly known as the atomic age, the emission of radiation in the form of rays or particles called radioactivity. There are many deposits of uranium in Pakistan and their uses cause much positive as well as negative impact on humans and environment. Uranium having a potential to cause a spectrum of adverse health effects ranging from renal failure and diminished bone growth to damage to DNA, because uranium possesses both chemical toxicity as well as radioactivity, assessing the relative contributions of each to its toxic profile is difficult. By knowing these risk factors, there is a need of hour that we should work on the impacts of uranium in environment and humans to devise new techniques and measurements for the reduction of uranium pollution and this will be helpful for others to devise more acceptable and facile methods in future. In this article, aimed to discuss toxicology of uranium, sources of emission as well as their impact on human health and environment.