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THE USE OF PLANT EXTRACT IN A MOUSE MODEL OF DEPRESSION: A REVIEW

Alamgeer, Taseer Ahmad,Iradat Hussain, Muhammad Naveed Mushtaq, Nadeem Irshad1, , Muhammad Wasim, Sultan Uallah, Maria Mukkaram

Depression is a mood disorder which is among the most dominant forms of psychiatric disorders and a major cause for morbidity and mortality. Since, many synthetic drugs are being used as anti-depressant, but due to adverse effects it leads to patient non-compliance. Thus, there is a need to search for plants oriented anti-depressant drugs and also develop a suitable animal model to clearly elucidate its effects. A number of medicinal plants have shown anti-depressant activities. This review attention is towards plant extract and its use in best animal model which will certainly highlights their influence on the development of novel therapeutic drugs.