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Similarity of hierarchical structured clustering in human and neuronal interactions and on DNA: Structural and functional analogies.

Magnus S Magnusson

Hierarchical structured clustering (HSC) seems characteristic of the structure of the universe balancing a small number of forces, some pulling others pushing apart, the self-similar fractal distribution of matter in the universe thus reflecting HST rather than just dispersion or clumping. HSC also characterizes a proposed pattern type, called T-pattern, detected in the temporal organization of many kinds of verbal and non-verbal human, animal and neuronal behavior and interactions and is also characteristic of the structure of DNA. Functional analogies seem to exist between the occurrence of T-patterns in “cell city” and in human cities. Structural self-similarity over many levels of biological organization suggests the possibility of a unified (mathematical, bioinformatics and system biological) approach. The T-patternis described as a repeated hierarchical and self-similar tree structure based on a single non-terminal relation, called a critical interval (CI) relationship. Theinstancesof a T-pattern may be seen as repeated statistical pseudo-fractal objects characterized by statistically significant translation symmetry.