select ad.sno,ad.journal,ad.title,ad.author_names,ad.abstract,ad.abstractlink,j.j_name,vi.* from articles_data ad left join journals j on j.journal=ad.journal left join vol_issues vi on vi.issue_id_en=ad.issue_id where ad.sno_en='10032' and ad.lang_id='10' and j.lang_id='10' and vi.lang_id='10'
ஐ.எஸ்.எஸ்.என்: 2169-0138
Toshihiko Tashima
By definition of term, it is thought that drug’s pharmacophores function only to have within an organism.pharmacophores also possess pharmacokinetic aspects such as absorption, distribution, metabolism, excretion, and toxicity (ADMET). Thus, it is important to include pharmacokinetically advantageous elements in drug design. Both chemical knowledge and biological knowledge are needed for such drug design. In this short review, multifunctionality of drug’s pharmacophores is described with three examples (pravastatin, penicillin, and enalapril).