மருந்து வடிவமைத்தல்: திறந்த அணுகல்
திறந்த அணுகல்

சுருக்கம்

Multifunctionality of Drug's Pharmacophores within an Organism

Toshihiko Tashima

By definition of term, it is thought that drug’s pharmacophores function only to have within an organism.pharmacophores also possess pharmacokinetic aspects such as absorption, distribution, metabolism, excretion, and toxicity (ADMET). Thus, it is important to include pharmacokinetically advantageous elements in drug design. Both chemical knowledge and biological knowledge are needed for such drug design. In this short review, multifunctionality of drug’s pharmacophores is described with three examples (pravastatin, penicillin, and enalapril).