select ad.sno,ad.journal,ad.title,ad.author_names,ad.abstract,ad.abstractlink,j.j_name,vi.* from articles_data ad left join journals j on j.journal=ad.journal left join vol_issues vi on vi.issue_id_en=ad.issue_id where ad.sno_en='51274' and ad.lang_id='10' and j.lang_id='10' and vi.lang_id='10' Fatal Myocarditis in a Male with Systemic Sclerosis | 51274
மருத்துவ மற்றும் பரிசோதனை இருதயவியல்

மருத்துவ மற்றும் பரிசோதனை இருதயவியல்
திறந்த அணுகல்

ஐ.எஸ்.எஸ்.என்: 2155-9880

சுருக்கம்

Fatal Myocarditis in a Male with Systemic Sclerosis

Thouraya Ben Salem*, Molka Tougorti, Imed Ben Ghorbel and Mohamed Habib Houman

Cardiac involvements in systemic sclerosis have a poor outcome. We report here a case of 28 year-old-man with history of systemic sclerosis developing a fatal myocarditis. Initially patient has disabling joint manifestation. Systemic sclerosis is diagnosed after progressive development of cutaneous, pulmonary, and gastrointestinal manifestations. One year after systemic sclerosis diagnosis, our patient develops heart failure signs when he is already treated with methotrexate (15 mg/week) and coticosteroids (15 mg/day). Echocardiography show global hypokinesia with low left ventricular ejection fraction (32%). Natriuretic peptides and troponin levels are high. Anti-centromere and anti-SRP antibodies are positive. Corticosteroids dose is increased to 1 mg/kg/day, and methotrexate was given 25 mg/week without improvement. Cyclophosphamide was started but patient died within six months. Despite immunosuppressive therapy, myocarditis outcome is poor since patient was in heart failure at presentation, and has anti-SRP antibodies.

மறுப்பு: இந்த சுருக்கமானது செயற்கை நுண்ணறிவு கருவிகளைப் பயன்படுத்தி மொழிபெயர்க்கப்பட்டது மற்றும் இன்னும் மதிப்பாய்வு செய்யப்படவில்லை அல்லது சரிபார்க்கப்படவில்லை.
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