ஐ.எஸ்.எஸ்.என்: 2155-9554
Lafuente Cevallos Lizeth Veronica*, Urena Lopez Valeria Alexandra, Lascano Gallegos Nathalie, Palacios Alvarez Santiago Alberto
Epidermolysis Bullosa Acquisita (EBA) is a chronic autoimmune subepidermal blistering disease developed after damage to type VII collagen by autoantibodies. Type VII collagen is the major component of anchoring fibrils in the sub-lamina densa hemidesmosomes of the skin and squamous mucosas. The worldwide incidence is estimated between 0.2-0.5/million inhabitants per year. Two major clinical variants have been described: the mechanobullous, and the inflammatory EBA.