எலும்பு ஆராய்ச்சி இதழ்
திறந்த அணுகல்

சுருக்கம்

Dystrophinopathy

Aakshi Kainthola

Early-onset Duchenne muscular dystrophy (DMD) is characterised by delays in motor milestones such as walking independently and rising up from a supine position. A waddling stride and difficulties ascending stairs, sprinting, jumping, and rising up from a crouching position are all symptoms of proximal weakness. DMD progresses quickly, and by the age of 12, afflicted children are wheelchair-bound. After the age of 18, approximately everyone with DMD develops cardiomyopathy. Respiratory problems and worsening cardiomyopathy are frequent causes of mortality in people in their third decade.