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Developing Electronic-nose Technologies for Clinical Practice

Alphus Dan Wilson

The development of relatively simple gas-sensing devices with sensor arrays capable of constructing molecular profiles of complex Volatile Organic Compound (VOC) metabolites from clinical samples, based on production of healthy or disease-specific digital signature patterns, may soon help to revolutionize diagnostic procedures in clinical practice. This mini-review summarizes the development of recent portable electronic-nose (e-nose) technologies as new diagnostic tools with the potential for accelerating clinical procedures to facilitate non-invasive early disease diagnoses, improving the speed and accuracy of Point-Of-Care Testing (POCT); yielding more effective treatments and significantly improving prognoses.