select ad.sno,ad.journal,ad.title,ad.author_names,ad.abstract,ad.abstractlink,j.j_name,vi.* from articles_data ad left join journals j on j.journal=ad.journal left join vol_issues vi on vi.issue_id_en=ad.issue_id where ad.sno_en='50117' and ad.lang_id='10' and j.lang_id='10' and vi.lang_id='10' Detection of Complications Following Intravenous Immunoglobu | 50117
ஜர்னல் ஆஃப் கிளினிக்கல் அண்ட் செல்லுலார் இம்யூனாலஜி

ஜர்னல் ஆஃப் கிளினிக்கல் அண்ட் செல்லுலார் இம்யூனாலஜி
திறந்த அணுகல்

ஐ.எஸ்.எஸ்.என்: 2155-9899

சுருக்கம்

Detection of Complications Following Intravenous Immunoglobulins Infusion in A Cohort of Egyptian Children

Aisha Elmarsafy, Nermeen M Galal, Shrouk M Abdallah and Ilham Youssry

Background: Intravenous immunoglobulins (IVIG) are scarce biological products that are increasingly used in an expanding variety of disorders. Tolerance to infusions is usually well but adverse events, including serious ones have been reported.

Objectives: The study aimed at detection of adverse events following IVIG infusion in relation to preparation, dosing regimen, duration and infusion hours with identification of patients at risk of developing complications.

Material and Methods: An observational study was conducted on a cohort of 55 patients (birth-18 years) who received 62 infusion sessions for different disease conditions over a period of six months. Monitored clinical evaluation and laboratory assessments were done with follow up 7-10 days following the infusions.

Results: Adverse events occurred in 37.1% of IVIG infusion sessions ranging from mild reactions as skin rash, fever to more severe anaphylactoid ones as serum sickness, anemia and acute renal failure. Infusion rate and the presence of risk factors were strong predicting variables for numerous reactions.

Conclusion: Proper justification for use of IVIG with close monitoring of dosage and infusion rate during administration can avoid some reactions. Weighing benefits against hazards is crucial in high risk patients to minimize complications.

மறுப்பு: இந்த சுருக்கமானது செயற்கை நுண்ணறிவு கருவிகளைப் பயன்படுத்தி மொழிபெயர்க்கப்பட்டது மற்றும் இன்னும் மதிப்பாய்வு செய்யப்படவில்லை அல்லது சரிபார்க்கப்படவில்லை.
Top