பெண்ணோயியல் & மகப்பேறியல்
திறந்த அணுகல்

சுருக்கம்

Correlation between Mitral (E/A), Pulmonary (At/Et) Ratios in Doppler Mode and the Biological Marker of Fetal Lung Maturity (Lecithin/Sphingomyelin Ratio)

Caloone J, Cortet M, Boisson-Gaudin C, Chicaud B, Chambon V, Rudigoz RC and Huissoud C

Objective: To analyse the correlation between Doppler fetal heart indicators such as mitral ratio (E/A), acceleration time/ejection time (AT/ET) ratio in the main of pulmonary artery to the lecithin/sphingomyelin ratio (L/S) dosed in the amniotic fluid.

Material and Methods: Prospective study including singletons between 24 and 39 weeks of gestation, for whom caesarean delivery was planned. E/A and AT/ET ratios were realised during the 24 hours before birth. The L/S ratio was assayed by thin-layer chromatography, from samples of amniotic fluid.

Results: Thirty fetus were included, for a median (IQR) gestational age of 37 weeks (33.8-38.7) and a median weight birth of 2600 g (1888-3140). The correlation between the E/A and L/S ratios was positive: r = 0.56 (95% CI [0.24–0.76], p<0.01) while the correlation between AT/ET and L/S ratios was negative: r = - 0.44 (95% CI [(-0.69) – (-0.10)], p<0.01). The median E/A ratio in the hyaline membrane disease group was lower than in the group without (0.55 vs. 0.78, p< 0.01), while the median AT/ET ratio was higher (0.31 vs. 0.21, p= 0.011).

Conclusion: The E/A, AT/ET, and L/S ratios are correlated. Further studies are necessary to confirm the interest of these Doppler heart indicators to assess the fetal lung maturity.