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Commentary on Sensitivity of Immune Response vs . Stress Resistance

Weiya Zhang, Xinyun Li

Stress resistance refers to adaptability to harsh environments and is therefore negatively correlated with immune response sensitivity. The article “Three functional mutation sites affect the immune response of pigs through altering the expression pattern and IgV domain of the CD4 protein” identified three key SNPs that affect the CD4 protein antigen presentation function and analyzed the reasons for the differences in stress resistance of different breeds of pigs. We provided a short commentary on the research in this article, which will help the reader's understanding of disease resistance breeding and the treatment of immune-related diseases