ஐ.எஸ்.எஸ்.என்: 2157-7013
Felicia Hanzu and Xavier Escoté
Lee and colleagues have shown that CDK4 plays a central role in glucose homeostasis. Insulin activates cyclin D1–CDK4, leading to a decrease in circulating glucose as a consequence of the down-regulation of main genes involved in liver gluconeogenesis.