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Are Nodular Goiter Patients Likely to have a Poor Quality of Life after Thyroidectomy, if they Received Hormonal Suppressive Therapy for a Long Time before Surgery?

Emil Iskandarov*, Nazrin Agayeva

Background: The Quality of life of patients with benign thyroid nodules after surgical procedures is particularly important in evaluating the long-term results.

Aim: To compare the Quality of life of patients previously treated with L-Thyroxine and then underwent thyroidectomy, and whose surgery was introduced without hormonal suppressive therapy.

Materials and methods: The outcomes of 174 patients with nodular goiter who underwent thyroidectomy were comparatively analyzed. Eighty-eight patients did not receive any hormonal treatment before surgery (basic group); eighty-six patients were treated with L-thyroxin for 1 year, and when hormonal suppressive therapy was identified as ineffective, were underwent surgery (control group). The Quality of Life was calculated with the SF-36 Questionnaire, 3, 6, and 12 months after surgery, and compared among groups.

Results: In the basic group, 3 months after thyroidectomy only Mental Health parameters were higher than in the control group. 6 months after surgery Physical Activity (84.5 ± 1.8 points), Body Pain (65.1 ± 2.5 points), and Emotional Status (52.1 ± 1.3 points) were better compared to the control group (p<0.05). 12 months after the operation, all parameters of the quality of life of the main group of patients were evaluated with a higher score than the control group.

Conclusion: The quality of life in the control group was significantly low (p<0.05).