select ad.sno,ad.journal,ad.title,ad.author_names,ad.abstract,ad.abstractlink,j.j_name,vi.* from articles_data ad left join journals j on j.journal=ad.journal left join vol_issues vi on vi.issue_id_en=ad.issue_id where ad.sno_en='28828' and ad.lang_id='10' and j.lang_id='10' and vi.lang_id='10' Alcohol Versus Cannabinoids: A Review of their Opposite Neur | 28828
ஜர்னல் ஆஃப் ஆல்கஹாலிசம் & போதைப்பொருள் சார்பு

ஜர்னல் ஆஃப் ஆல்கஹாலிசம் & போதைப்பொருள் சார்பு
திறந்த அணுகல்

ஐ.எஸ்.எஸ்.என்: 2329-6488

சுருக்கம்

Alcohol Versus Cannabinoids: A Review of their Opposite Neuro-Immunomodulatory Effects and Future Therapeutic Potentials

Marisela Agudelo, Madhavan PN, Gloria Figueroa BS, Gianna C and Karla M

Due to the legalization of marijuana and the increased demand for cannabis and alcohol consumption, research efforts highlighting the biomedical consequences of the use of alcohol and cannabinoids are not only relevant to the substance abuse scientific field, but are also of public health interest. Moreover, an overview of the recent literature about alcohol and cannabinoids neuro-immunomodulatory effects highlighting their future therapeutic potentials will provide a significant contribution to science and medicine. Therefore, in the current review, we will first discuss briefly the prevalence of alcohol and marijuana abuse, followed by a discussion on the individual effects of alcohol and cannabinoids on the immune system; then, we will focus on the role of endo-cannabinoids on the alcohol-induced inflammatory effects. The final section will highlight the therapeutic potential of cannabinoid receptors and the novel strategies to treat alcohol dependence as determined by in vitro, in vivo and clinical studies. In addition, the review also incorporates cytokine array data obtained from human Monocyte-Derived Dendritic Cells, providing a different perspective on the alcohol and cannabinoid abuse divergent effects on cytokine production. The ultimate objective of the current review is a discussion of the individual effects of alcohol and marijuana abuse on inflammation and the combined effects of alcohol consumption and cannabinoid receptor signaling leading to the understanding of novel therapeutic strategies to treat alcohol dependence using cannabinoid receptor targeting.

மறுப்பு: இந்த சுருக்கமானது செயற்கை நுண்ணறிவு கருவிகளைப் பயன்படுத்தி மொழிபெயர்க்கப்பட்டது மற்றும் இன்னும் மதிப்பாய்வு செய்யப்படவில்லை அல்லது சரிபார்க்கப்படவில்லை.
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