ஐ.எஸ்.எஸ்.என்: 2472-1077
Soumyadip Gharai
In antiquity, the mania and melancholia were considered disturbances of the soul [1]. Until the early nineteenth century, no relationship between crises of mania and depression was established. Later, they began to be considered as a single disease, receiving the name of manic-depressive insanity [2].